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Aspartate-β-Hydroxylase: A Promising Target to Limit the Local Invasiveness of Colorectal Cancer

Colorectal cancer’s (CRC) ability to invade local tissues and lymph nodes and generate distant metastases is the key for TNM classification. Aspartate-β-hydroxylase (ASPH), a transmembrane protein that catalyzes Notch receptors and ligand activation, is involved in tumor invasion. Because Notch is i...

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Detalles Bibliográficos
Autores principales: Benelli, Roberto, Costa, Delfina, Mastracci, Luca, Grillo, Federica, Olsen, Mark Jon, Barboro, Paola, Poggi, Alessandro, Ferrari, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226058/
https://www.ncbi.nlm.nih.gov/pubmed/32295249
http://dx.doi.org/10.3390/cancers12040971