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Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment
The functions of the annexin family of proteins involve binding to Ca(2+), lipid membranes, other proteins, and RNA, and the annexins share a common folded core structure at the C terminus. Annexin A11 (AnxA11) has a long N-terminal region, which is predicted to be disordered, binds RNA, and forms m...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226064/ https://www.ncbi.nlm.nih.gov/pubmed/32344647 http://dx.doi.org/10.3390/biom10040660 |