Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment

The functions of the annexin family of proteins involve binding to Ca(2+), lipid membranes, other proteins, and RNA, and the annexins share a common folded core structure at the C terminus. Annexin A11 (AnxA11) has a long N-terminal region, which is predicted to be disordered, binds RNA, and forms m...

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Detalles Bibliográficos
Autores principales: Lillebostad, Peder A. G., Raasakka, Arne, Hjellbrekke, Silje J., Patil, Sudarshan, Røstbø, Trude, Hollås, Hanne, Sakya, Siri A., Szigetvari, Peter D., Vedeler, Anni, Kursula, Petri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226064/
https://www.ncbi.nlm.nih.gov/pubmed/32344647
http://dx.doi.org/10.3390/biom10040660

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