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PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer

The identification of colorectal cancer (CRC) molecular targets is needed for the development of drugs that improve patient survival. We investigated the functional role of phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), a de novo purine...

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Detalles Bibliográficos
Autores principales: Agarwal, Sumit, Chakravarthi, Balabhadrapatruni V. S. K., Behring, Michael, Kim, Hyung-Gyoon, Chandrashekar, Darshan S., Gupta, Nirzari, Bajpai, Prachi, Elkholy, Amr, Balasubramanya, Sai A. H., Hardy, Cherlene, Diffalha, Sameer Al, Varambally, Sooryanarayana, Manne, Upender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226071/
https://www.ncbi.nlm.nih.gov/pubmed/32218208
http://dx.doi.org/10.3390/cancers12040772