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A Novel Serine Protease Inhibitor PE-BBI Ameliorates Cockroach Extract-Mediated Airway Epithelial Barrier Dysfunction

Epithelial barrier dysfunction, characteristic of allergic airway disease may be, at least in part, due to the action of allergen-associated protease activities. Cockroach allergy is a major global health issue, with cockroaches containing considerable serine trypsin-like protease (TLP) activity. Th...

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Detalles Bibliográficos
Autores principales: Reihill, James A., Ouyang, Xuan, Yang, Zhixuan, Douglas, Lisa E. J., Zhou, Mei, Chen, Tianbao, Martin, S. Lorraine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226075/
https://www.ncbi.nlm.nih.gov/pubmed/32231120
http://dx.doi.org/10.3390/biom10040515