Cargando…
A Novel Serine Protease Inhibitor PE-BBI Ameliorates Cockroach Extract-Mediated Airway Epithelial Barrier Dysfunction
Epithelial barrier dysfunction, characteristic of allergic airway disease may be, at least in part, due to the action of allergen-associated protease activities. Cockroach allergy is a major global health issue, with cockroaches containing considerable serine trypsin-like protease (TLP) activity. Th...
Autores principales: | Reihill, James A., Ouyang, Xuan, Yang, Zhixuan, Douglas, Lisa E. J., Zhou, Mei, Chen, Tianbao, Martin, S. Lorraine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226075/ https://www.ncbi.nlm.nih.gov/pubmed/32231120 http://dx.doi.org/10.3390/biom10040515 |
Ejemplares similares
-
Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide–PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer
por: Lyu, Peng, et al.
Publicado: (2018) -
Novel inhibitors and activity-based probes targeting serine proteases
por: Ferguson, Timothy E. G., et al.
Publicado: (2022) -
Promotion of a Protease–Antiprotease Imbalance in the Airways through Chronic Vaping
por: Martin, S. Lorraine, et al.
Publicado: (2019) -
Novel Inhibitors and Activity-Based Probes Targeting Trypsin-Like Serine Proteases
por: Ferguson, Timothy E. G., et al.
Publicado: (2022) -
Cockroach protease allergen induces allergic airway inflammation via epithelial cell activation
por: Kale, Sagar L., et al.
Publicado: (2017)