Leptin Signaling Contributes to Aromatase Inhibitor Resistant Breast Cancer Cell Growth and Activation of Macrophages

Obesity represents a risk factor for breast cancer development and therapy resistance, but the molecular players underling these links are unclear. Here, we identify a role for the obesity-cytokine leptin in sustaining aromatase inhibitor (AI) resistant growth and progression in breast cancer. Using...

Descripción completa

Detalles Bibliográficos
Autores principales: Gelsomino, Luca, Giordano, Cinzia, La Camera, Giusi, Sisci, Diego, Marsico, Stefania, Campana, Antonella, Tarallo, Roberta, Rinaldi, Antonio, Fuqua, Suzanne, Leggio, Antonella, Grande, Fedora, Bonofiglio, Daniela, Andò, Sebastiano, Barone, Ines, Catalano, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226081/
https://www.ncbi.nlm.nih.gov/pubmed/32260113
http://dx.doi.org/10.3390/biom10040543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226081/
https://www.ncbi.nlm.nih.gov/pubmed/32260113
http://dx.doi.org/10.3390/biom10040543

Ejemplares similares