Strained Conformations of Nucleosides in Active Sites of Nucleoside Phosphorylases

Nucleoside phosphorylases catalyze the reversible phosphorolysis of nucleosides to heterocyclic bases, giving α-d-ribose-1-phosphate or α-d-2-deoxyribose-1-phosphate. These enzymes are involved in salvage pathways of nucleoside biosynthesis. The level of these enzymes is often elevated in tumors, wh...

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Detalles Bibliográficos
Autores principales: Il’icheva, Irina A., Polyakov, Konstantin M., Mikhailov, Sergey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226091/
https://www.ncbi.nlm.nih.gov/pubmed/32260512
http://dx.doi.org/10.3390/biom10040552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226091/
https://www.ncbi.nlm.nih.gov/pubmed/32260512
http://dx.doi.org/10.3390/biom10040552

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