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Tumor Ulceration, Reduced Infiltration of CD8-Lymphocytes, High Neutrophil-to-CD8-Lymphocyte Ratio and Absence of MC Virus are Negative Prognostic Markers for Patients with Merkel Cell Carcinoma

(1) Background: Merkel cell carcinoma (MCC) is caused by the Merkel cell polyomavirus and UV radiation. Understanding of the underlying biology is limited, but identification of prognostic markers may lead to better prognostic stratification for the patients. (2) Methods: Ninety patients diagnosed w...

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Detalles Bibliográficos
Autores principales: Naseri, Simon, Steiniche, Torben, Bæhr Georgsen, Jeanette, Thomsen, Rune, Ladekarl, Morten, Heje, Martin, Engberg Damsgaard, Tine, Bønnelykke-Behrndtz, Marie Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226107/
https://www.ncbi.nlm.nih.gov/pubmed/32268526
http://dx.doi.org/10.3390/cancers12040888