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Role of BET Inhibitors in Triple Negative Breast Cancers

Bromodomain and extraterminal domain (BET) proteins have evolved as key multifunctional super-regulators that control gene expression. These proteins have been shown to upregulate transcriptional machinery leading to over expression of genes involved in cell proliferation and carcinogenesis. Based o...

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Detalles Bibliográficos
Autores principales: Khandekar, Durga, Tiriveedhi, Venkataswarup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226117/
https://www.ncbi.nlm.nih.gov/pubmed/32218352
http://dx.doi.org/10.3390/cancers12040784