Reductive Evolution and Diversification of C5-Uracil Methylation in the Nucleic Acids of Mollicutes

The C5-methylation of uracil to form 5-methyluracil (m(5)U) is a ubiquitous base modification of nucleic acids. Four enzyme families have converged to catalyze this methylation using different chemical solutions. Here, we investigate the evolution of 5-methyluracil synthase families in Mollicutes, a...

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Detalles Bibliográficos
Autores principales: Sirand-Pugnet, Pascal, Brégeon, Damien, Béven, Laure, Goyenvalle, Catherine, Blanchard, Alain, Rose, Simon, Grosjean, Henri, Douthwaite, Stephen, Hamdane, Djemel, de Crécy-Lagard, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226160/
https://www.ncbi.nlm.nih.gov/pubmed/32290235
http://dx.doi.org/10.3390/biom10040587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226160/
https://www.ncbi.nlm.nih.gov/pubmed/32290235
http://dx.doi.org/10.3390/biom10040587

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