Betulinic Acid-Mediated Tuning of PERK/CHOP Signaling by Sp1 Inhibition as a Novel Therapeutic Strategy for Glioblastoma

Patients with glioblastoma are at high risk of local recurrences after initial treatment with standard therapy, and recurrent tumor cells appear to be resistant to first-line drug temozolomide. Thus, finding an effective second-line agent for treating primary and recurrent glioblastomas is critical....

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Detalles Bibliográficos
Autores principales: Lo, Wei-Lun, Hsu, Tsung-I, Yang, Wen-Bin, Kao, Tzu-Jen, Wu, Ming-Hsiao, Huang, Yung-Ning, Yeh, Shiu-Hwa, Chuang, Jian-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226172/
https://www.ncbi.nlm.nih.gov/pubmed/32326583
http://dx.doi.org/10.3390/cancers12040981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226172/
https://www.ncbi.nlm.nih.gov/pubmed/32326583
http://dx.doi.org/10.3390/cancers12040981

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