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Relationship among DNA double‐strand break (DSB), DSB repair, and transcription prevents genome instability and cancer

DNA double‐strand break (DSB) is a serious type of DNA damage and is known to trigger multiple responses within cells. In these responses, novel relationships among DSB, DSB repair, and transcription machineries are created. First, transcription is repressed if DSB occurs near or at the transcriptio...

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Detalles Bibliográficos
Autores principales: Ui, Ayako, Chiba, Natsuko, Yasui, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226179/
https://www.ncbi.nlm.nih.gov/pubmed/32232911
http://dx.doi.org/10.1111/cas.14404