Potent Anticancer Effect of the Natural Steroidal Saponin Gracillin Is Produced by Inhibiting Glycolysis and Oxidative Phosphorylation-Mediated Bioenergetics

Metabolic rewiring to utilize aerobic glycolysis is a hallmark of cancer. However, recent findings suggest the role of mitochondria in energy generation in cancer cells and the metabolic switch to oxidative phosphorylation (OXPHOS) in response to the blockade of glycolysis. We previously demonstrate...

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Detalles Bibliográficos
Autores principales: Min, Hye-Young, Pei, Honglan, Hyun, Seung Yeob, Boo, Hye-Jin, Jang, Hyun-Ji, Cho, Jaebeom, Kim, Ji Hye, Son, Jaekyoung, Lee, Ho-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226187/
https://www.ncbi.nlm.nih.gov/pubmed/32276500
http://dx.doi.org/10.3390/cancers12040913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226187/
https://www.ncbi.nlm.nih.gov/pubmed/32276500
http://dx.doi.org/10.3390/cancers12040913

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