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Targeting claudin‐4 enhances chemosensitivity in breast cancer

Triple negative breast cancer (TNBC) is characterized by highly aggressive phenotype, limited treatment options and a poor prognosis. In the present study, we examined the therapeutic effect of anti–claudin (CLDN)‐4 extracellular domain antibody, 4D3, on TNBC. When the expression of CLDN4 and CLDN1...

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Detalles Bibliográficos
Autores principales: Luo, Yi, Kishi, Shingo, Sasaki, Takamitsu, Ohmori, Hitoshi, Fujiwara‐Tani, Rina, Mori, Shiori, Goto, Kei, Nishiguchi, Yukiko, Mori, Takuya, Kawahara, Isao, Kondoh, Masuo, Kuniyasu, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226188/
https://www.ncbi.nlm.nih.gov/pubmed/32086991
http://dx.doi.org/10.1111/cas.14361