Gene rearrangements of MLL and RUNX1 sporadically occur in normal CD34(+) cells under cytokine stimulation

Gene rearrangements of MLL/KMT2A or RUNX1 are the major cause of therapy‐related leukemia. Moreover, MLL rearrangements are the major cause of infant leukemia, and RUNX1 rearrangements are frequently detected in cord blood. These genes are sensitive to topoisomerase II inhibitors, and various genes...

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Detalles Bibliográficos
Autores principales: Harada, Yuka, Shingai, Naoki, Ding, Ye, Sadato, Daichi, Hayashi, Yoshihiro, Yamaguchi, Masaki, Okuyama, Yoshiki, Shimoyama, Tatsu, Ohashi, Kazuteru, Harada, Hironori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226195/
https://www.ncbi.nlm.nih.gov/pubmed/32216001
http://dx.doi.org/10.1111/cas.14392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226195/
https://www.ncbi.nlm.nih.gov/pubmed/32216001
http://dx.doi.org/10.1111/cas.14392

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