Long-Distance Phasing of a Tentative “Enhancer” Single-Nucleotide Polymorphism With CYP2D6 Star Allele Definitions

BACKGROUND: The CYP2D6 gene locus has been extensively studied over decades, yet a portion of variability in CYP2D6 activity cannot be explained by known sequence variations within the gene, copy number variation, or structural rearrangements. It was proposed that rs5758550, located 116 kb downstrea...

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Detalles Bibliográficos
Autores principales: Boone, Erin C., Wang, Wendy Y., Gaedigk, Roger, Cherner, Mariana, Bérard, Anick, Leeder, J. Steven, Miller, Neil A., Gaedigk, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226225/
https://www.ncbi.nlm.nih.gov/pubmed/32457600
http://dx.doi.org/10.3389/fphar.2020.00486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226225/
https://www.ncbi.nlm.nih.gov/pubmed/32457600
http://dx.doi.org/10.3389/fphar.2020.00486

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