Targeting the Acidic Tumor Microenvironment: Unexpected Pro-Neoplastic Effects of Oral NaHCO(3) Therapy in Murine Breast Tissue

The acidic tumor microenvironment modifies malignant cell behavior. Here, we study consequences of the microenvironment in breast carcinomas. Beginning at carcinogen-based breast cancer induction, we supply either regular or NaHCO(3)-containing drinking water to female C57BL/6j mice. We evaluate uri...

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Detalles Bibliográficos
Autores principales: Voss, Ninna C. S., Dreyer, Thomas, Henningsen, Mikkel B., Vahl, Pernille, Honoré, Bent, Boedtkjer, Ebbe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226235/
https://www.ncbi.nlm.nih.gov/pubmed/32268614
http://dx.doi.org/10.3390/cancers12040891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226235/
https://www.ncbi.nlm.nih.gov/pubmed/32268614
http://dx.doi.org/10.3390/cancers12040891

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