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Structural and Biophysical Insights into the Function of the Intrinsically Disordered Myc Oncoprotein

Myc is a transcription factor driving growth and proliferation of cells and involved in the majority of human tumors. Despite a huge body of literature on this critical oncogene, our understanding of the exact molecular determinants and mechanisms that underlie its function is still surprisingly lim...

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Detalles Bibliográficos
Autores principales: Beaulieu, Marie-Eve, Castillo, Francisco, Soucek, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226237/
https://www.ncbi.nlm.nih.gov/pubmed/32331235
http://dx.doi.org/10.3390/cells9041038