Folate‐appended cyclodextrin carrier targets ovarian cancer cells expressing the proton‐coupled folate transporter

Folate receptor alpha (FRα) is overexpressed in >80% of epithelial ovarian cancer (EOC). Accordingly, folate is attracting attention as a targeting ligand for EOC. For EOC patients, paclitaxel (PTX) is generally used as a first‐line chemotherapeutic agent in combination with platinum‐based drugs....

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Detalles Bibliográficos
Autores principales: Saito, Shinichi, Koya, Yoshihiro, Kajiyama, Hiroaki, Yamashita, Mamoru, Kikkawa, Fumitaka, Nawa, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226238/
https://www.ncbi.nlm.nih.gov/pubmed/32154964
http://dx.doi.org/10.1111/cas.14379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226238/
https://www.ncbi.nlm.nih.gov/pubmed/32154964
http://dx.doi.org/10.1111/cas.14379

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