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Folate‐appended cyclodextrin carrier targets ovarian cancer cells expressing the proton‐coupled folate transporter
Folate receptor alpha (FRα) is overexpressed in >80% of epithelial ovarian cancer (EOC). Accordingly, folate is attracting attention as a targeting ligand for EOC. For EOC patients, paclitaxel (PTX) is generally used as a first‐line chemotherapeutic agent in combination with platinum‐based drugs....
Autores principales: | Saito, Shinichi, Koya, Yoshihiro, Kajiyama, Hiroaki, Yamashita, Mamoru, Kikkawa, Fumitaka, Nawa, Akihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226238/ https://www.ncbi.nlm.nih.gov/pubmed/32154964 http://dx.doi.org/10.1111/cas.14379 |
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