Reduced Tumorigenicity of Mouse ES Cells and the Augmented Anti-Tumor Therapeutic Effects under Parg Deficiency

PolyADP-ribosylation is a post-translational modification of proteins, and poly(ADP-ribose) (PAR) polymerase (PARP) family proteins synthesize PAR using NAD as a substrate. Poly(ADP-ribose) glycohydrolase (PARG) functions as the main enzyme for the degradation of PAR. In this study, we investigated...

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Detalles Bibliográficos
Autores principales: Sonoda, Yuki, Sasaki, Yuka, Gunji, Akemi, Shirai, Hidenori, Araki, Tomonori, Imamichi, Shoji, Onodera, Takae, Rydén, Anna-Margareta, Watanabe, Masatoshi, Itami, Jun, Honda, Takuya, Ashizawa, Kazuto, Nakao, Kazuhiko, Masutani, Mitsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226256/
https://www.ncbi.nlm.nih.gov/pubmed/32344695
http://dx.doi.org/10.3390/cancers12041056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226256/
https://www.ncbi.nlm.nih.gov/pubmed/32344695
http://dx.doi.org/10.3390/cancers12041056

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