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Curcumin β‐D‐glucuronide exhibits anti–tumor effects on oxaliplatin‐resistant colon cancer with less toxicity in vivo

The NF‐kappa B (NF‐κB) pathway plays a pivotal role in tumor progression and chemoresistance, and its inhibition has been shown to suppress tumor growth in a variety of preclinical models. Recently, we succeeded in synthesizing a water‐soluble injectable type of curcumin β‐D‐glucuronide (CMG), which...

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Detalles Bibliográficos
Autores principales: Ozawa‐Umeta, Hitomi, Kishimoto, Atsuhiro, Imaizumi, Atsushi, Hashimoto, Tadashi, Asakura, Tadashi, Kakeya, Hideaki, Kanai, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226283/
https://www.ncbi.nlm.nih.gov/pubmed/32163218
http://dx.doi.org/10.1111/cas.14383