Dexamethasone Attenuates X-Ray-Induced Activation of the Autotaxin-Lysophosphatidate-Inflammatory Cycle in Breast Tissue and Subsequent Breast Fibrosis

We recently showed that radiation-induced DNA damage in breast adipose tissue increases autotaxin secretion, production of lysophosphatidate (LPA) and expression of LPA(1/2) receptors. We also established that dexamethasone decreases autotaxin production and LPA signaling in non-irradiated adipose t...

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Detalles Bibliográficos
Autores principales: Meng, Guanmin, Wuest, Melinda, Tang, Xiaoyun, Dufour, Jennifer, McMullen, Todd P.W., Wuest, Frank, Murray, David, Brindley, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226295/
https://www.ncbi.nlm.nih.gov/pubmed/32325715
http://dx.doi.org/10.3390/cancers12040999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226295/
https://www.ncbi.nlm.nih.gov/pubmed/32325715
http://dx.doi.org/10.3390/cancers12040999

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