Chlorpromazine Induces Basolateral Aquaporin-2 Accumulation via F-Actin Depolymerization and Blockade of Endocytosis in Renal Epithelial Cells

We previously showed that in polarized Madin–Darby canine kidney (MDCK) cells, aquaporin-2 (AQP2) is continuously targeted to the basolateral plasma membrane from which it is rapidly retrieved by clathrin-mediated endocytosis. It then undertakes microtubule-dependent transcytosis toward the apical p...

Descripción completa

Detalles Bibliográficos
Autores principales: Bouley, Richard, Yui, Naofumi, Terlouw, Abby, Cheung, Pui W., Brown, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226349/
https://www.ncbi.nlm.nih.gov/pubmed/32340337
http://dx.doi.org/10.3390/cells9041057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226349/
https://www.ncbi.nlm.nih.gov/pubmed/32340337
http://dx.doi.org/10.3390/cells9041057

Ejemplares similares