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Chlorpromazine Induces Basolateral Aquaporin-2 Accumulation via F-Actin Depolymerization and Blockade of Endocytosis in Renal Epithelial Cells

We previously showed that in polarized Madin–Darby canine kidney (MDCK) cells, aquaporin-2 (AQP2) is continuously targeted to the basolateral plasma membrane from which it is rapidly retrieved by clathrin-mediated endocytosis. It then undertakes microtubule-dependent transcytosis toward the apical p...

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Detalles Bibliográficos
Autores principales:	Bouley, Richard, Yui, Naofumi, Terlouw, Abby, Cheung, Pui W., Brown, Dennis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226349/ https://www.ncbi.nlm.nih.gov/pubmed/32340337 http://dx.doi.org/10.3390/cells9041057

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