The Role of Alternative Lengthening of Telomeres Mechanism in Cancer: Translational and Therapeutic Implications

Telomere maintenance mechanisms (i.e., telomerase activity (TA) and the alternative lengthening of telomere (ALT) mechanism) contribute to tumorigenesis by providing unlimited proliferative capacity to cancer cells. Although the role of either telomere maintenance mechanisms seems to be equivalent i...

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Detalles Bibliográficos
Autores principales: Recagni, Marta, Bidzinska, Joanna, Zaffaroni, Nadia, Folini, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226354/
https://www.ncbi.nlm.nih.gov/pubmed/32290440
http://dx.doi.org/10.3390/cancers12040949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226354/
https://www.ncbi.nlm.nih.gov/pubmed/32290440
http://dx.doi.org/10.3390/cancers12040949

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