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Aspirin: A Suicide Inhibitor of Carbonic Anhydrase II

Carbonic anhydrase II (CAII) is a metalloenzyme that catalyzes the reversible hydration/dehydration of CO(2)/HCO(3)(−). In addition, CAII is attributed to other catalytic reactions, including esterase activity. Aspirin (acetyl-salicylic acid), an everyday over-the-counter drug, has both ester and ca...

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Detalles Bibliográficos
Autores principales: Andring, Jacob, Combs, Jacob, McKenna, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226357/
https://www.ncbi.nlm.nih.gov/pubmed/32244293
http://dx.doi.org/10.3390/biom10040527