Drug Development Targeting the Ubiquitin–Proteasome System (UPS) for the Treatment of Human Cancers

Cancer cells are characterized by a higher rate of protein turnover and greater demand for protein homeostasis compared to normal cells. In this scenario, the ubiquitin–proteasome system (UPS), which is responsible for the degradation of over 80% of cellular proteins within mammalian cells, becomes...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xiaonan, Linder, Stig, Bazzaro, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226376/
https://www.ncbi.nlm.nih.gov/pubmed/32272746
http://dx.doi.org/10.3390/cancers12040902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226376/
https://www.ncbi.nlm.nih.gov/pubmed/32272746
http://dx.doi.org/10.3390/cancers12040902

Ejemplares similares