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Revisiting Cancer Stem Cells as the Origin of Cancer-Associated Cells in the Tumor Microenvironment: A Hypothetical View from the Potential of iPSCs

The tumor microenvironment (TME) has an essential role in tumor initiation and development. Tumor cells are considered to actively create their microenvironment during tumorigenesis and tumor development. The TME contains multiple types of stromal cells, cancer-associated fibroblasts (CAFs), Tumor e...

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Detalles Bibliográficos
Autores principales: Osman, Amira, Afify, Said M., Hassan, Ghmkin, Fu, Xiaoying, Seno, Akimasa, Seno, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226406/
https://www.ncbi.nlm.nih.gov/pubmed/32260363
http://dx.doi.org/10.3390/cancers12040879