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Acquired Immunity Is Not Essential for Radiation-Induced Heart Dysfunction but Exerts a Complex Impact on Injury

While radiation therapy (RT) can improve cancer outcomes, it can lead to radiation-induced heart dysfunction (RIHD) in patients with thoracic tumors. This study examines the role of adaptive immune cells in RIHD. In Salt-Sensitive (SS) rats, image-guided whole-heart RT increased cardiac T-cell infil...

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Detalles Bibliográficos
Autores principales: Schlaak, Rachel A., Frei, Anne, Fish, Brian L., Harmann, Leanne, Gasperetti, Tracy, Pipke, Jamie L., Sun, Yunguang, Rui, Hallgeir, Flister, Michael J., Gantner, Benjamin N., Bergom, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226421/
https://www.ncbi.nlm.nih.gov/pubmed/32316187
http://dx.doi.org/10.3390/cancers12040983