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Half Way to Hypusine—Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase

Deoxyhypusine synthase (DHS) is a transferase enabling the formation of deoxyhypusine, which is the first, rate-limiting step of a unique post-translational modification: hypusination. DHS catalyses the transfer of a 4-aminobutyl moiety of polyamine spermidine to a specific lysine of eukaryotic tran...

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Detalles Bibliográficos
Autores principales: Wątor, Elżbieta, Wilk, Piotr, Grudnik, Przemysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226451/
https://www.ncbi.nlm.nih.gov/pubmed/32235505
http://dx.doi.org/10.3390/biom10040522