Therapeutic Strategies and Biomarkers to Modulate PARP Activity for Targeted Cancer Therapy

Poly-(ADP-ribose) polymerase 1 (PARP1) is commonly known for its vital role in DNA damage response and repair. However, its enzymatic activity has been linked to a plethora of physiological and pathophysiological transactions ranging from cellular proliferation, survival and death. For instance, mal...

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Detalles Bibliográficos
Autores principales: Singh, Naveen, Pay, S. Louise, Bhandare, Snehal B., Arimpur, Udhaya, Motea, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226473/
https://www.ncbi.nlm.nih.gov/pubmed/32295316
http://dx.doi.org/10.3390/cancers12040972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226473/
https://www.ncbi.nlm.nih.gov/pubmed/32295316
http://dx.doi.org/10.3390/cancers12040972

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