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Therapeutic Strategies and Biomarkers to Modulate PARP Activity for Targeted Cancer Therapy
Poly-(ADP-ribose) polymerase 1 (PARP1) is commonly known for its vital role in DNA damage response and repair. However, its enzymatic activity has been linked to a plethora of physiological and pathophysiological transactions ranging from cellular proliferation, survival and death. For instance, mal...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226473/ https://www.ncbi.nlm.nih.gov/pubmed/32295316 http://dx.doi.org/10.3390/cancers12040972 |