The Receptor Tyrosine Kinase RON and Its Isoforms as Therapeutic Targets in Ewing Sarcoma

The receptor tyrosine kinase (RTK) RON is linked to an aggressive metastatic phenotype of carcinomas. While gaining interest as a therapeutic target, RON remains unstudied in sarcomas. In Ewing sarcoma, we identified RON among RTKs conferring resistance to insulin-like growth factor-1 receptor (IGF1...

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Detalles Bibliográficos
Autores principales: Berning, Philipp, Hennemann, Carolin, Tulotta, Claudia, Schaefer, Christiane, Lechtape, Birgit, Hotfilder, Marc, El Gourari, Yassmine, Jürgens, Heribert, Snaar-Jagalska, Ewa, Hempel, Georg, Dirksen, Uta, Potratz, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226494/
https://www.ncbi.nlm.nih.gov/pubmed/32272784
http://dx.doi.org/10.3390/cancers12040904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226494/
https://www.ncbi.nlm.nih.gov/pubmed/32272784
http://dx.doi.org/10.3390/cancers12040904

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