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Helicobacter pylori Avoids the Critical Activation of NLRP3 Inflammasome-Mediated Production of Oncogenic Mature IL-1β in Human Immune Cells

Helicobacter pylori persistently colonizes the human stomach, and is associated with inflammation-induced gastric cancer. Bacterial crosstalk with the host immune system produces various inflammatory mediators and subsequent reactions in the host, but not bacterial clearance. Interleukin-1β (IL-1β)...

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Detalles Bibliográficos
Autores principales: Pachathundikandi, Suneesh Kumar, Blaser, Nicole, Bruns, Heiko, Backert, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226495/
https://www.ncbi.nlm.nih.gov/pubmed/32230726
http://dx.doi.org/10.3390/cancers12040803