A STAT3 of Addiction: Adipose Tissue, Adipocytokine Signalling and STAT3 as Mediators of Metabolic Remodelling in the Tumour Microenvironment

Metabolic remodelling of the tumour microenvironment is a major mechanism by which cancer cells survive and resist treatment. The pro-oncogenic inflammatory cascade released by adipose tissue promotes oncogenic transformation, proliferation, angiogenesis, metastasis and evasion of apoptosis. STAT3 h...

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Detalles Bibliográficos
Autores principales: Kadye, Rose, Stoffels, Mihlali, Fanucci, Sidne, Mbanxa, Siso, Prinsloo, Earl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226520/
https://www.ncbi.nlm.nih.gov/pubmed/32331320
http://dx.doi.org/10.3390/cells9041043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226520/
https://www.ncbi.nlm.nih.gov/pubmed/32331320
http://dx.doi.org/10.3390/cells9041043

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