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A STAT3 of Addiction: Adipose Tissue, Adipocytokine Signalling and STAT3 as Mediators of Metabolic Remodelling in the Tumour Microenvironment
Metabolic remodelling of the tumour microenvironment is a major mechanism by which cancer cells survive and resist treatment. The pro-oncogenic inflammatory cascade released by adipose tissue promotes oncogenic transformation, proliferation, angiogenesis, metastasis and evasion of apoptosis. STAT3 h...
Autores principales: | Kadye, Rose, Stoffels, Mihlali, Fanucci, Sidne, Mbanxa, Siso, Prinsloo, Earl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226520/ https://www.ncbi.nlm.nih.gov/pubmed/32331320 http://dx.doi.org/10.3390/cells9041043 |
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