The Inhibition of Wnt Restrain KRAS(G12V)-Driven Metastasis in Non-Small-Cell Lung Cancer

The KRAS mutations have been an obstacle to identify therapeutic targets in cancer treatment. In this work, we clarified the distinct metastasis pattern of non-small-cell lung carcinoma (NSCLC) induced by KRAS(G12V)/KRAS(G12D) mutations and inhibited the KRAS(G12V) mediated metastasis by Wnt inhibit...

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Detalles Bibliográficos
Autores principales: Hung, Pei-Shan, Huang, Ming-Hung, Kuo, Yuan-Yeh, Yang, James Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226522/
https://www.ncbi.nlm.nih.gov/pubmed/32244355
http://dx.doi.org/10.3390/cancers12040837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226522/
https://www.ncbi.nlm.nih.gov/pubmed/32244355
http://dx.doi.org/10.3390/cancers12040837

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