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Unique Role of Histone Methyltransferase PRDM8 in the Tumorigenesis of Virus-Negative Merkel Cell Carcinoma

Merkel cell carcinoma (MCC) is a deadly skin cancer, and about 80% of its cases have been shown to harbor integrated Merkel polyomavirus in the tumor cell genome. Viral oncoproteins expressed in the tumor cells are considered as the oncogenic factors of these virus-positive Merkel cell carcinoma (VP...

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Detalles Bibliográficos
Autores principales: Orouji, Elias, Peitsch, Wiebke K., Orouji, Azadeh, Houben, Roland, Utikal, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226539/
https://www.ncbi.nlm.nih.gov/pubmed/32344701
http://dx.doi.org/10.3390/cancers12041057