Citrate Mediates Crosstalk between Mitochondria and the Nucleus to Promote Human Mesenchymal Stem Cell In Vitro Osteogenesis

Citrate, generated in the mitochondria, is a key metabolite that might link metabolism with signaling, chromatin structure and transcription to orchestrate mesenchymal stem cells (MSCs) fate determination. Based on a detailed morphological analysis of 3D reconstruction of mitochondria and nuclei in...

Descripción completa

Detalles Bibliográficos
Autores principales: Morganti, Claudia, Bonora, Massimo, Marchi, Saverio, Ferroni, Letizia, Gardin, Chiara, Wieckowski, Mariusz R., Giorgi, Carlotta, Pinton, Paolo, Zavan, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226543/
https://www.ncbi.nlm.nih.gov/pubmed/32326298
http://dx.doi.org/10.3390/cells9041034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226543/
https://www.ncbi.nlm.nih.gov/pubmed/32326298
http://dx.doi.org/10.3390/cells9041034

Ejemplares similares