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Citrate Mediates Crosstalk between Mitochondria and the Nucleus to Promote Human Mesenchymal Stem Cell In Vitro Osteogenesis
Citrate, generated in the mitochondria, is a key metabolite that might link metabolism with signaling, chromatin structure and transcription to orchestrate mesenchymal stem cells (MSCs) fate determination. Based on a detailed morphological analysis of 3D reconstruction of mitochondria and nuclei in...
Autores principales: | Morganti, Claudia, Bonora, Massimo, Marchi, Saverio, Ferroni, Letizia, Gardin, Chiara, Wieckowski, Mariusz R., Giorgi, Carlotta, Pinton, Paolo, Zavan, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226543/ https://www.ncbi.nlm.nih.gov/pubmed/32326298 http://dx.doi.org/10.3390/cells9041034 |
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