MiRNAs Targeting Double Strand DNA Repair Pathways Lurk in Genomically Unstable Rare Fragile Sites and Determine Cancer Outcomes

Double strand break (DSB) repair mechanisms guard genome integrity and their deterioration causes genomic instability. Common and rare fragile sites (CFS and RFS, respectively) are particularly vulnerable to instability, and there is an inverse correlation between fragile site (FS) expression and DS...

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Detalles Bibliográficos
Autores principales: Marquardt, Stephan, Richter, Christin, Pützer, Brigitte M., Logotheti, Stella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226545/
https://www.ncbi.nlm.nih.gov/pubmed/32260317
http://dx.doi.org/10.3390/cancers12040876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226545/
https://www.ncbi.nlm.nih.gov/pubmed/32260317
http://dx.doi.org/10.3390/cancers12040876

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