Extreme Diversity of IgGs Against Histones, DNA, and Myelin Basic Protein in the Cerebrospinal Fluid and Blood of Patients with Multiple Sclerosis

It was recently shown that IgGs from sera of multiple sclerosis (MS) patients are active in the hydrolysis of DNA and myelin basic protein (MBP). We first analyzed the relative concentration of antibodies against five histones (H1, H2a, H2b, H3, and H4) in the cerebrospinal fluid (CSF) and serum of...

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Detalles Bibliográficos
Autores principales: Kostrikina, Irina A., Buneva, Valentina N., Granieri, Enrico, Nevinsky, Georgy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226582/
https://www.ncbi.nlm.nih.gov/pubmed/32325782
http://dx.doi.org/10.3390/biom10040630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226582/
https://www.ncbi.nlm.nih.gov/pubmed/32325782
http://dx.doi.org/10.3390/biom10040630

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