Chimeric Antigen Receptor Cell Therapy: Overcoming Obstacles to Battle Cancer

Chimeric antigen receptors (CAR) are fusion proteins engineered from antigen recognition, signaling, and costimulatory domains that can be used to reprogram T cells to specifically target tumor cells expressing specific antigens. Current CAR-T cell technology utilizes the patient’s own T cells to st...

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Detalles Bibliográficos
Autores principales: Petty, Amy J., Heyman, Benjamin, Yang, Yiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226583/
https://www.ncbi.nlm.nih.gov/pubmed/32244520
http://dx.doi.org/10.3390/cancers12040842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226583/
https://www.ncbi.nlm.nih.gov/pubmed/32244520
http://dx.doi.org/10.3390/cancers12040842

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