Exploring Biased Agonism at FPR1 as a Means to Encode Danger Sensing †

Ligand-based selectivity in signal transduction (biased signaling) is an emerging field of G protein-coupled receptor (GPCR) research and might allow the development of drugs with targeted activation profiles. Human formyl peptide receptor 1 (FPR1) is a GPCR that detects potentially hazardous states...

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Detalles Bibliográficos
Autores principales: Gröper, Jieny, König, Gabriele M., Kostenis, Evi, Gerke, Volker, Raabe, Carsten A., Rescher, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226602/
https://www.ncbi.nlm.nih.gov/pubmed/32340221
http://dx.doi.org/10.3390/cells9041054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226602/
https://www.ncbi.nlm.nih.gov/pubmed/32340221
http://dx.doi.org/10.3390/cells9041054

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