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Extracellular Vesicle Biomarkers Reveal Inhibition of Neuroinflammation by Infliximab in Association with Antidepressant Response in Adults with Bipolar Depression

Accumulating evidence suggests that neuroinflammation is involved in bipolar disorder (BD) pathogenesis. The tumor necrosis factor-alpha (TNF-α) antagonist infliximab was recently reported to improve depressive symptoms in a subpopulation of individuals with BD and history of childhood maltreatment....

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Detalles Bibliográficos
Autores principales: Mansur, Rodrigo B., Delgado-Peraza, Francheska, Subramaniapillai, Mehala, Lee, Yena, Iacobucci, Michelle, Rodrigues, Nelson, Rosenblat, Joshua D., Brietzke, Elisa, Cosgrove, Victoria E., Kramer, Nicole E., Suppes, Trisha, Raison, Charles L., Chawla, Sahil, Nogueras-Ortiz, Carlos, McIntyre, Roger S., Kapogiannis, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226726/
https://www.ncbi.nlm.nih.gov/pubmed/32268604
http://dx.doi.org/10.3390/cells9040895