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A Conserved LIR Motif in Connexins Mediates Ubiquitin-Independent Binding to LC3/GABARAP Proteins

Gap junctions (GJ) are specialized cell-cell contacts formed by connexins (Cxs), which provide direct communication between adjacent cells. Cx43 ubiquitination has been suggested to induce the internalization of GJs, as well as the recruitment of the autophagy receptor p62 to mediate binding to LC3B...

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Detalles Bibliográficos
Autores principales: Catarino, Steve, Ribeiro-Rodrigues, Teresa M, Sá Ferreira, Rita, Ramalho, José, Abert, Christine, Martens, Sascha, Girão, Henrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226732/
https://www.ncbi.nlm.nih.gov/pubmed/32272685
http://dx.doi.org/10.3390/cells9040902