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Lamin Mutations Cause Increased YAP Nuclear Entry in Muscle Stem Cells

Mutations in the LMNA gene, encoding the nuclear envelope A-type lamins, are responsible for muscular dystrophies, the most severe form being the LMNA-related congenital muscular dystrophy (L-CMD), with severe defects in myonucleus integrity. We previously reported that L-CMD mutations compromise th...

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Detalles Bibliográficos
Autores principales: Owens, Daniel J., Fischer, Martina, Jabre, Saline, Moog, Sophie, Mamchaoui, Kamel, Butler-Browne, Gillian, Coirault, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226749/
https://www.ncbi.nlm.nih.gov/pubmed/32231000
http://dx.doi.org/10.3390/cells9040816