Cargando…
Lamin Mutations Cause Increased YAP Nuclear Entry in Muscle Stem Cells
Mutations in the LMNA gene, encoding the nuclear envelope A-type lamins, are responsible for muscular dystrophies, the most severe form being the LMNA-related congenital muscular dystrophy (L-CMD), with severe defects in myonucleus integrity. We previously reported that L-CMD mutations compromise th...
Autores principales: | Owens, Daniel J., Fischer, Martina, Jabre, Saline, Moog, Sophie, Mamchaoui, Kamel, Butler-Browne, Gillian, Coirault, Catherine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226749/ https://www.ncbi.nlm.nih.gov/pubmed/32231000 http://dx.doi.org/10.3390/cells9040816 |
Ejemplares similares
-
Nuclear Mechanotransduction in Skeletal Muscle
por: Jabre, Saline, et al.
Publicado: (2021) -
Lamin-Related Congenital Muscular Dystrophy Alters Mechanical Signaling and Skeletal Muscle Growth
por: Owens, Daniel J., et al.
Publicado: (2020) -
YAP-Mediated Mechanotransduction in Skeletal Muscle
por: Fischer, Martina, et al.
Publicado: (2016) -
Lamins and nesprin-1 mediate inside-out mechanical coupling in muscle cell precursors through FHOD1
por: Schwartz, Christine, et al.
Publicado: (2017) -
Nitric Oxide (NO) and Duchenne Muscular Dystrophy: NO Way to Go?
por: Timpani, Cara A., et al.
Publicado: (2020)